Tag Archives: bococizumab

November, 2016

  • 1 November

    Pfizer Discontinues Development of its Investigational PCSK9 Inhibitor

    Tuesday, November 1, 2016 – 6:30am EDT — Pfizer Inc. announced today the discontinuation of the global clinical development program for bococizumab, its investigational Proprotein Convertase Subtilisin Kexin type 9 inhibitor (PCSK9i). The totality of clinical information now available for bococizumab, taken together with the evolving treatment and market landscape for …

April, 2016

  • 1 April

    Pfizer’s PCSK9 Inhibitor Succeeds in its Second Late-Stage Study

    NEW YORK–(BUSINESS WIRE)–Pfizer Inc. announced that the Phase 3 SPIRE-AI (AutoInjector) trial of the investigational Proprotein Convertase Subtilisin Kexin type 9 inhibitor (PCSK9i) bococizumab administered with a pre-filled pen met its co-primary endpoints: percent change from baseline in low-density lipoprotein cholesterol (LDL-C) reduction at 12 weeks compared to placebo and …