Tag Archives: CAR-T cell

April, 2018

5 April
Pfizer and Allogene Partner for Expedited Development of CAR T Immuno-Oncology Portfolio

NEW YORK & SOUTH SAN FRANCISCO–(BUSINESS WIRE)–Pfizer Inc. (NYSE:PFE) and Allogene Therapeutics, Inc. (Allogene) today announced that the two companies have entered into an asset contribution agreement for Pfizer’s portfolio of assets related to allogeneic chimeric antigen receptor T cell (CAR T) therapy, an investigational immune cell therapy approach to …
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11 December
Celgene and bluebird bio’s CAR T Cell Therapy Demonstrates Positive Results in Multiple Myeloma Trial

SUMMIT, N.J. & CAMBRIDGE, Mass.–(BUSINESS WIRE)– Celgene Corporation (NASDAQ: CELG) and bluebird bio, Inc. (Nasdaq: BLUE) today announced that updated results from the ongoing CRB-401 Phase 1 clinical study of bb2121, an investigational anti-B-cell maturation antigen (BCMA) CAR T cell therapy, in 21 patients with late-stage relapsed/refractory multiple myeloma will be presented in an oral presentation …
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19 October
FDA Approves Kite’s CAR-T Therapy Yescarta for the Treatment of Large B-Cell Lymphoma

FOSTER CITY, Calif. & SANTA MONICA, Calif.–(BUSINESS WIRE)–Kite, a Gilead Company, (Nasdaq: GILD) today announced that the U.S. Food and Drug Administration (FDA) has granted regular approval to Yescarta™ (axicabtagene ciloleucel), the first chimeric antigen receptor T cell (CAR T) therapy for the treatment of adult patients with relapsed or …
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19 December
Juno Therapeutics Defeats Kite Pharma’s Challenge to CAR T-Cell Patent

SEATTLE–(BUSINESS WIRE)–Juno Therapeutics, Inc. (NASDAQ: JUNO), a biopharmaceutical company developing innovative cellular immunotherapies for the treatment of cancer, today announced that it has defeated an attempt to invalidate a patent exclusively licensed by Juno that covers, among other things, a chimeric antigen receptor (CAR) T cell used for the treatment …
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22 April
Juno’s Investigational CAR T Cell Product Candidates Show Promise in Patients with B-Cell and Mesothelioma Cancers

SEATTLE–(BUSINESS WIRE)–Apr. 20, 2016– Juno Therapeutics, Inc. (NASDAQ: JUNO), a biopharmaceutical company focused on re-engaging the body’s immune system to revolutionize the treatment of cancer, today announced, in partnership with its collaborators, early clinical data from two oral presentations for two product candidates at the American Association for Cancer Research …
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13 January
Juno Therapeutics Acquires AbVitro, Adding Next-Generation Single Cell Sequencing Capabilities

SEATTLE–(BUSINESS WIRE)–Jan. 11, 2016– Juno Therapeutics, Inc. (Nasdaq: JUNO), a biopharmaceutical company focused on re-engaging the body’s immune system to revolutionize the treatment of cancer, announced today that it has acquired AbVitro, Inc., a privately held biotechnology company based in Boston, Massachusetts. The acquisition provides Juno with a leading next-generation …
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7 December
Novartis Announces Positive Results for its CAR-T Therapy

Basel, December 6, 2015 – Findings from an ongoing Phase IIa study to evaluate the safety and efficacy of investigational chimeric antigen receptor T cell (CART) therapy CTL019 in certain types of relapsed or refractory (r/r) non-Hodgkin lymphoma will be presented in an oral session at the 57th American Society …
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